TRIP10 抗体 (Middle Region)
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北京 101111
Quick Overview for TRIP10 抗体 (Middle Region) (ABIN1109339)
抗原
See all TRIP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- FEGSSEGTIS MAEGEDLSLM EEDKGDGWTR VRRKEGGEGY VPTSYLRVTL
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交叉反应 (详细)
- Species reactivity (expected):Rat, Mouse, Bovine, Zebrafish, African clawed frog, RabbitSpecies reactivity (tested):Human
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纯化方法
- Purified using peptide immunoaffinity column
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免疫原
- The immunogen for anti-TRIP10 antibody: synthetic peptide directed towards the middle region of human TRIP10.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))
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别名
- TRIP10
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背景
- TRIP10 is required for translocation of GLUT4 to the plasma membrane in response to insulin signaling and to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. It binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules and also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. TRIP10 is further required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells and may be required for the lysosomal retention of FASLG/FASL.Synonyms: CIP4, Cdc42-interacting protein 4, Protein Felic, STOT, STP, Salt tolerant protein, TRIP-10, Thyroid receptor-interacting protein 10
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基因ID
- 9322
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NCBI登录号
- NP_004231
抗原
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