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TRIP10 抗体 (Middle Region)

This anti-TRIP10 antibody is a 兔 多克隆 antibody detecting TRIP10 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼 和 非洲爪蟾.
产品编号 ABIN1109339
发货至: 中国

Quick Overview for TRIP10 抗体 (Middle Region) (ABIN1109339)

抗原

See all TRIP10 抗体
TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

适用

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人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 非洲爪蟾

宿主

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克隆类型

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多克隆

标记

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This TRIP10 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    FEGSSEGTIS MAEGEDLSLM EEDKGDGWTR VRRKEGGEGY VPTSYLRVTL

    交叉反应 (详细)

    Species reactivity (expected):Rat, Mouse, Bovine, Zebrafish, African clawed frog, RabbitSpecies reactivity (tested):Human

    纯化方法

    Purified using peptide immunoaffinity column

    免疫原

    The immunogen for anti-TRIP10 antibody: synthetic peptide directed towards the middle region of human TRIP10.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Add 50 μL of distilled water to a final concentration of 1 mg/mL.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原

    TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

    别名

    TRIP10

    背景

    TRIP10 is required for translocation of GLUT4 to the plasma membrane in response to insulin signaling and to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. It binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules and also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. TRIP10 is further required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells and may be required for the lysosomal retention of FASLG/FASL.Synonyms: CIP4, Cdc42-interacting protein 4, Protein Felic, STOT, STP, Salt tolerant protein, TRIP-10, Thyroid receptor-interacting protein 10

    基因ID

    9322

    NCBI登录号

    NP_004231
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