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TRIM13 抗体 (Middle Region)

TRIM13 适用: 人, 小鼠, 大鼠, Cow WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109332
发货至: 中国
  • 抗原 See all TRIM13 抗体
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    抗原表位
    • 15
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 34
    • 19
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, Cow
    宿主
    • 46
    • 3
    克隆类型
    • 47
    • 2
    多克隆
    标记
    • 19
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM13 antibody is un-conjugated
    应用范围
    • 37
    • 23
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    DTLETSKRKS LQLLTKDSDK VKEFFEKLQH TLDQKKNEIL SDFETMKLAV
    交叉反应 (详细)
    Species reactivity (expected):Rat, Mouse, BovineSpecies reactivity (tested):Human
    纯化方法
    Purified using peptide immunoaffinity column
    免疫原
    The immunogen for anti-TRIIM13 antibody: synthetic peptide directed towards the middle region of human TRIM13
    Top Product
    Discover our top product TRIM13 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Add 50 μL of distilled water to a final concentration of 1 mg/mL.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    别名
    TRIM13 / RNF77 (TRIM13 产品)
    别名
    TRIM13 antibody, RFP2 antibody, CAR antibody, DLEU5 antibody, LEU5 antibody, RNF77 antibody, 3110001L12Rik antibody, Rfp2 antibody, tripartite motif containing 13 antibody, ret finger protein 2 antibody, tripartite motif-containing 13 antibody, TRIM13 antibody, LOC100338599 antibody, Trim13 antibody
    背景
    TRIM13 is an E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. TRIM13 enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation, regulates ER stress-induced autophagy, and may act as a tumor suppressor.Synonyms: B-cell chronic lymphocytic leukemia tumor suppressor Leu5, LEU5, Leukemia-associated protein 5, Putative tumor suppressor RFP2, RFP2, RING finger protein 77, Tripartite motif-containing protein 13
    基因ID
    10206
    NCBI登录号
    NP_005789
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