TRIM13 抗体 (Middle Region)
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北京 101111
Quick Overview for TRIM13 抗体 (Middle Region) (ABIN1109332)
抗原
See all TRIM13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- DTLETSKRKS LQLLTKDSDK VKEFFEKLQH TLDQKKNEIL SDFETMKLAV
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交叉反应 （详细）
- Species reactivity (expected):Rat, Mouse, BovineSpecies reactivity (tested):Human
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纯化方法
- Purified using peptide immunoaffinity column
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免疫原
- The immunogen for anti-TRIIM13 antibody: synthetic peptide directed towards the middle region of human TRIM13
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anti-Tripartite Motif Containing 13 (TRIM13) (Middle Region) antibody
TRIM13 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 40-310) antibodyTRIM13 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (Middle Region) antibodyTRIM13 适用: 人, 小鼠, 大鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 1-100) antibodyTRIM13 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 165-214) antibodyTRIM13 适用: 人, 大鼠, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 40-310) antibodyTRIM13 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 1-100) antibodyTRIM13 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 1-100) antibodyTRIM13 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 181-230) antibodyTRIM13 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 51-100) antibodyTRIM13 适用: 人, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- TRIM13 (Tripartite Motif Containing 13 (TRIM13))
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别名
- TRIM13 / RNF77
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背景
- TRIM13 is an E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. TRIM13 enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation, regulates ER stress-induced autophagy, and may act as a tumor suppressor.Synonyms: B-cell chronic lymphocytic leukemia tumor suppressor Leu5, LEU5, Leukemia-associated protein 5, Putative tumor suppressor RFP2, RFP2, RING finger protein 77, Tripartite motif-containing protein 13
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基因ID
- 10206
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NCBI登录号
- NP_005789
抗原
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