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TRIM13 抗体 (Middle Region)

TRIM13 适用: 人, 小鼠, 大鼠, Cow WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109332
发货至: 中国
  • 抗原 See all TRIM13 抗体
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    抗原表位
    • 15
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 32
    • 21
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, Cow
    宿主
    • 44
    • 3
    克隆类型
    • 45
    • 2
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM13 antibody is un-conjugated
    应用范围
    • 35
    • 19
    • 13
    • 13
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    DTLETSKRKS LQLLTKDSDK VKEFFEKLQH TLDQKKNEIL SDFETMKLAV
    交叉反应 (详细)
    Species reactivity (expected):Rat, Mouse, BovineSpecies reactivity (tested):Human
    纯化方法
    Purified using peptide immunoaffinity column
    免疫原
    The immunogen for anti-TRIIM13 antibody: synthetic peptide directed towards the middle region of human TRIM13
    Top Product
    Discover our top product TRIM13 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Add 50 μL of distilled water to a final concentration of 1 mg/mL.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    别名
    TRIM13 / RNF77 (TRIM13 产品)
    背景
    TRIM13 is an E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. TRIM13 enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation, regulates ER stress-induced autophagy, and may act as a tumor suppressor.Synonyms: B-cell chronic lymphocytic leukemia tumor suppressor Leu5, LEU5, Leukemia-associated protein 5, Putative tumor suppressor RFP2, RFP2, RING finger protein 77, Tripartite motif-containing protein 13
    基因ID
    10206
    NCBI登录号
    NP_005789
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