TRIB3 抗体 (N-Term)
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Quick Overview for TRIB3 抗体 (N-Term) (ABIN1109329)
抗原
See all TRIB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Reacts with Human 39 kDa TRIB-3 protein.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Synthetic peptide derived from N-terminal domain of Human TRIB-3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore in distilled water.
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缓冲液
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
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注意事项
- Avoid repeated freezing and thawing.
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- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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别名
- TRIB3
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背景
- A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.Synonyms: NIPK, SKIP3, TRB-3, TRB3, Tribbles homolog 3
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基因ID
- 57761
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NCBI登录号
- NP_066981
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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