Transglutaminase 2 抗体
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北京 101111
Quick Overview for Transglutaminase 2 抗体 (ABIN1109303)
抗原
See all Transglutaminase 2 (TGM2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 (详细)
- Species reactivity (tested):Human, Guinea Pig.
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纯化方法
- Affinity Chromatography on Protein A
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亚型
- IgG3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore in distilled water.
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缓冲液
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
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: "Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells." in: The EMBO journal, Vol. 39, Issue 8, pp. e102166, (2020) (PubMed).
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: "Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells." in: The EMBO journal, Vol. 39, Issue 8, pp. e102166, (2020) (PubMed).
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- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
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别名
- Transglutaminase-2
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背景
- Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
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途径
- Tube Formation, Thromboxane A2 Receptor Signaling
抗原
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