TJP2 抗体 (AA 411-467)
Quick Overview for TJP2 抗体 (AA 411-467) (ABIN1109264)
抗原
See all TJP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 411-467
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特异性
- This antibody recognizes human zona occludens 2 (ZO-2).
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Protein A
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免疫原
- Amino acids 411-467 of human ZO-2
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亚型
- Ig Fraction
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anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 307-669) antibody
TJP2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 951-1190) antibodyTJP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 1165-1183) antibodyTJP2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 121-218) antibodyTJP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (C-Term) antibodyTJP2 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 1-1190) antibodyTJP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (C-Term) antibodyTJP2 适用: 人, 大鼠, 犬, Cow, 豚鼠, 兔, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) (AA 468-517) antibodyTJP2 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) antibodyTJP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) antibodyTJP2 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, containing 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
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别名
- TJP2
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背景
- Zona occludens 2 (ZO-2) is an ~160 kDa tight junction protein belonging to the membrane-associated guanlyate kinase (MAGUK) family. Members of this family are involved in epithelial and endothelial intercellular junctions. They each contain at least one PSD95/Dlg/ZO-1 (PDZ) domain, a Src homology 3 (SH3) domain, and an enzymatically inactive guanylate kinase domain. PDZ domains are 90-amino acid protein-protein binding domains that recognize at least a 3-residue peptide motif in the COOH termini of their binding partners. PDZ domain-containing proteins, like ZO-2, typically act as scaffolding proteins that organize membrane receptors and cytosolic proteins into multimeric signaling complexes often at the sites of cell-cell contact. The effectiveness and stability of the epithelial barrier depends on a complex of proteins composing different intercellular junctions, which include tight junctions, adherens junctions, and desmosomes. ZO-2 can interact with zona occludens 1 (ZO-1). Furthermore, the PDZ2 domain of ZO-2 was shown to interact with connexin-43, the predominant connexin in epithelial and most other tissues which is involved in cell growth control and embryonic development.Synonyms: Tight junction protein 2, Tight junction protein ZO-2, X104, ZO2, Zona occludens protein 2, Zonula occludens protein 2
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基因ID
- 9414
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NCBI登录号
- NP_001164101
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UniProt
- Q9UDY2
抗原
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