TGFB2 抗体 (N-Term)
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Quick Overview for TGFB2 抗体 (N-Term) (ABIN1109226)
抗原
See all TGFB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Reacts with Human 48 kDa TGFB2 protein.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Synthetic peptide derived from N-terminal domain of Human TGFB2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore in distilled water.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
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- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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别名
- TGF-beta-2 (TGFB2)
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背景
- Transforming growth factor beta's (TGF beta's) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGF beta's mediate many cell-cell interactions that occur during embryonic development. Three TGF beta's have been identified in mammals. TGFB1, TGFB2 and TGFB3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFB3 protein has approximately 80 % identity to the mature region of both TGFB1 and TGFB2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.Synonyms: BSC-1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Polyergin, Transforming growth factor beta-2
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基因ID
- 7042
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NCBI登录号
- NP_001129071
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途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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