SYT1 抗体
Quick Overview for SYT1 抗体 (ABIN1109184)
抗原
See all SYT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with Synaptotagmin 1 and 2 (58 kDa/60 kDa) on Western blotting. Synaptotagmin 1 has a predicted molecular weight of 47 kDa but it migrates at ~65 kDa. It is reported that this clone (1D12) recognizes rat synaptotagmin residues (99-104 aa) in the reference number 17).
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交叉反应 （详细）
- Species reactivity (tested):Rat
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纯化方法
- Protein A agarose
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免疫原
- Chicken brain synaptic membrane
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亚型
- IgG2a
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anti-Synaptotagmin I (SYT1) (AA 1-422) antibody
SYT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 136-422) antibodySYT1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Synaptotagmin I (SYT1) (pSer309) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (AA 301-523) antibodySYT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2, without preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- SYT1 (Synaptotagmin I (SYT1))
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别名
- Synaptotagmin-1
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背景
- Synaptotagmins are a family of at least 15 Ca2+-binding, membrane-trafficking proteins that act as calcium sensors regulating neurotransmitter release. Synaptotagamins are expressed in both vesicular and plasma membranes where they are involved in lipid rearrangements required during synaptic vesicle fusion. Synaptotagmins also interact with calcium channels, sodium channels, b-SNAP, neurexins, and other neural proteins in the absence of Ca2+, suggesting a role in presynaptic functions. Synaptotagmins exhibit differential expression, with synaptotagmins 1-5 expressed primarily in neural and endocrine tissues. Northern blots in murine brain tissue suggest synaptotagmin 1 is primarily expressed in rostral brain regions but has low expression in regions related to motor functions.Synonyms: SVP65, SYT, SYT2, Synaptotagmin I, Synaptotagmin II, Synaptotagmin1, Synaptotagmin2, Synonyms: SYT1, SytI, SytII, p65
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基因ID
- 6857
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NCBI登录号
- NP_001129277
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UniProt
- P21579
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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