Synaptophysin 抗体
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Quick Overview for Synaptophysin 抗体 (ABIN1109181)
抗原
See all Synaptophysin (SYP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts with human and mouse Synaptophysin.
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纯化方法
- Protein A agarose
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免疫原
- Purified synaptic vesicle fraction from guinea pig cerebrum
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservtives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- Synaptophysin (SYP)
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别名
- Synaptophysin / SYP
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背景
- Synaptophysin (also referred to as SVP38 and p38) is an acidic Ca2+ binding glycoprotein of about 38 kDa which exist largely in synaptic vesicles. It has 4 transmembrane regions and is reported to be a major cholesterol-binding protein in synaptic vesicles. Synaptophysin may regulate synaptic exocytosis by competing with proteins such as SNAP25 and syntaxins to bind to synaptobrevin (vesicle-associated membrane protein, or VAMP). It may also participate in synaptic endocytosis, which contributes to rapid recycling of synaptic vesicle.Synonyms: Major synaptic vesicle protein p38, Neuroendocrine Marker
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基因ID
- 6855
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NCBI登录号
- NP_003170
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UniProt
- P08247
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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