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Synaptophysin 抗体

The 小鼠 单克隆 anti-Synaptophysin antibody (Clone 171B5) (ABIN1109181) specifically detects Synaptophysin in WB 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1109181
发货至: 中国
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Quick Overview for Synaptophysin 抗体 (ABIN1109181)

抗原

See all Synaptophysin (SYP) 抗体
Synaptophysin (SYP)

适用

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人, 小鼠

宿主

  • 78
  • 52
  • 3
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小鼠

克隆类型

  • 88
  • 46
单克隆

标记

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This Synaptophysin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

171B5
  • 特异性

    Reacts with human and mouse Synaptophysin.

    纯化方法

    Protein A agarose

    免疫原

    Purified synaptic vesicle fraction from guinea pig cerebrum

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. Contains no preservtives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store (in aliquots) at -20 °C.
  • 抗原

    Synaptophysin (SYP)

    别名

    Synaptophysin / SYP

    背景

    Synaptophysin (also referred to as SVP38 and p38) is an acidic Ca2+ binding glycoprotein of about 38 kDa which exist largely in synaptic vesicles. It has 4 transmembrane regions and is reported to be a major cholesterol-binding protein in synaptic vesicles. Synaptophysin may regulate synaptic exocytosis by competing with proteins such as SNAP25 and syntaxins to bind to synaptobrevin (vesicle-associated membrane protein, or VAMP). It may also participate in synaptic endocytosis, which contributes to rapid recycling of synaptic vesicle.Synonyms: Major synaptic vesicle protein p38, Neuroendocrine Marker

    基因ID

    6855

    NCBI登录号

    NP_003170

    UniProt

    P08247

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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