SUCNR1 抗体
Quick Overview for SUCNR1 抗体 (ABIN1109167)
抗原
See all SUCNR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of total SUCNR1 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide from Human SUCNR1. Epitope: Internal
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亚型
- IgG
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anti-Succinate Receptor 1 (SUCNR1) (AA 303-334) antibody
SUCNR1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Receptor 1 (SUCNR1) (Cytoplasmic Domain) antibodySUCNR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Succinate Receptor 1 (SUCNR1) (Internal Region) antibodySUCNR1 适用: 人, 大鼠, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Receptor 1 (SUCNR1) (AA 248-262), (Extracellular) antibodySUCNR1 适用: 大鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Succinate Receptor 1 (SUCNR1) (AA 248-262), (Extracellular) antibody (FITC)SUCNR1 适用: 大鼠 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-Succinate Receptor 1 (SUCNR1) (Cytoplasmic Domain) antibodySUCNR1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Succinate Receptor 1 (SUCNR1) (AA 100-149) antibodySUCNR1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Succinate Receptor 1 (SUCNR1) antibodySUCNR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Succinate Receptor 1 (SUCNR1) (AA 161-210) antibodySUCNR1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 50 % Glycerol, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SUCNR1 (Succinate Receptor 1 (SUCNR1))
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别名
- Succinate Receptor 1 / GPR91
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背景
- GPR91 (formerly known as P2U2) is a G protein-coupled, dicarboxylic acid succinate receptor. It has a high level of expression in the kidney, predominantly in the proximal tubules, and localizes to the plasma membrane. It has also been found at low levels in the liver and the spleen. GPR91 functions as a citric acid cycle intermediate succinate receptor. Two signaling pathways result from GPR91 activation, the pertussis-toxin-sensitive Gi/Go pathway and the pertussis-toxin-insensitive Gq pathway. Four amino acid residues are necessary for GPR91 activation by succinate: Arg 99, His 103, Arg 252 and Arg 281. GPR91 plays an important role in the succinate-induced hypertensive effect and may be involved in renovascular hypertension, a disease linked to diabetes, renal failure and atherosclerosis.Synonyms: G-protein coupled receptor 91, P2Y purinoceptor 1-like
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基因ID
- 56670
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NCBI登录号
- NP_149039
抗原
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