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SPTAN1 抗体

SPTAN1 适用: 人 WB, IHC (fro), EIA 宿主: 小鼠 Monoclonal AA6 unconjugated
产品编号 ABIN1109119
发货至: 中国
  • 抗原 See all SPTAN1 抗体
    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
    适用
    • 75
    • 39
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    宿主
    • 100
    • 15
    • 1
    小鼠
    克隆类型
    • 92
    • 24
    单克隆
    标记
    • 58
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    This SPTAN1 antibody is un-conjugated
    应用范围
    • 80
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    The antibody clone AA6 is specific to the 240 kDa Alpha-Fodrin molecule of all Mammalian nonerythroid cells and Chicken Alpha-Spectrin.
    交叉反应 (详细)
    Species reactivity (tested):Human, Rat, Chicken, Rabbit and Guinea Pig.
    纯化方法
    Ig Fraction
    免疫原
    Chicken red blood cell membranes purified by hypotonic lysis and mechanical enucleation. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
    克隆位点
    AA6
    亚型
    IgG1
    Top Product
    Discover our top product SPTAN1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide, 1.0 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
    别名
    Spectrin alpha Chain (Brain) / SPTAN1 (SPTAN1 产品)
    别名
    im:7157190 antibody, wu:fa20e05 antibody, wu:fb33g08 antibody, wu:fk32a10 antibody, zgc:112229 antibody, 2610027H02Rik antibody, Spna-2 antibody, Spna2 antibody, EIEE5 antibody, NEAS antibody, SPTA2 antibody, A2a antibody, IPF antibody, SPECA antibody, spectrin alpha, non-erythrocytic 1 antibody, spectrin, alpha, non-erythrocytic 1 antibody, SPTAN1 antibody, sptan1 antibody, Sptan1 antibody
    背景
    Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.Synonyms: Alpha-II spectrin, Fodrin alpha chain, SPTA2, Spectrin non-erythroid alpha chain
    基因ID
    374234
    NCBI登录号
    NP_001036003
    UniProt
    P07751
    途径
    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
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