Siglec H 抗体
The 大鼠 单克隆 anti-Siglec H antibody is suitable to detect Siglec H in samples from 小鼠. It has been validated for IHC (fro) 和 Func.
产品编号 ABIN1109009
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Siglec H 抗体 (ABIN1109009)
抗原
Siglec H
适用
小鼠
宿主
大鼠
克隆类型
单克隆
标记
This Siglec H antibody is un-conjugated
应用范围
Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
克隆位点
440c
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交叉反应 （详细）
- Species reactivity (tested):Mouse
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纯化方法
- Protein G
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亚型
- IgG2b
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anti-Siglec H (AA 109-309) antibody
适用: 小鼠 WB 宿主: 大鼠 Monoclonal ABM2B55 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % bovine serum albumin
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- Siglec H
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别名
- Siglec-H
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背景
- Siglec H is unique among Sialic acid-binding Ig-like lectins (Siglecs) proteins because it associates with the adaptor protein DAP12. DAP12 recognize certain viruses and CpG-DNA through TLR9, resulting in secretion of IFN-alpha, IL-12 and proinflammatory chemokines. Together these cytokines and chemokines recruite and activate NK cells and T cells as well as modulating the antigen presenting function of dendritic cells (DC). IPC themselves also function as antigen presenting cells that expand memory T cells and induce Th1 differentiation. Therefore IPC may provide a first line of host defense against viral infections by activating both innate and adaptive responses in vivo.
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UniProt
- Q3Y597
抗原
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