Siglec H 抗体
This anti-Siglec H antibody is a 大鼠 单克隆 antibody detecting Siglec H in IHC (fro) 和 Func. Suitable for 小鼠.
Quick Overview for Siglec H 抗体 (ABIN1109009)
抗原
Siglec H
适用
小鼠
宿主
大鼠
克隆类型
单克隆
标记
This Siglec H antibody is un-conjugated
应用范围
Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
克隆位点
440c
-
-
交叉反应 （详细）
- Species reactivity (tested):Mouse
-
纯化方法
- Protein G
-
亚型
- IgG2b
-
-
anti-Siglec H (AA 109-309) antibody
适用: 小鼠 WB 宿主: 大鼠 Monoclonal ABM2B55 unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % bovine serum albumin
-
储存条件
- 4 °C
-
储存方法
- Store at 2 - 8 °C.
-
-
- Siglec H
-
别名
- Siglec-H
-
背景
- Siglec H is unique among Sialic acid-binding Ig-like lectins (Siglecs) proteins because it associates with the adaptor protein DAP12. DAP12 recognize certain viruses and CpG-DNA through TLR9, resulting in secretion of IFN-alpha, IL-12 and proinflammatory chemokines. Together these cytokines and chemokines recruite and activate NK cells and T cells as well as modulating the antigen presenting function of dendritic cells (DC). IPC themselves also function as antigen presenting cells that expand memory T cells and induce Th1 differentiation. Therefore IPC may provide a first line of host defense against viral infections by activating both innate and adaptive responses in vivo.
-
UniProt
- Q3Y597
抗原
-
You are here:
