SHOX2 抗体 (Middle Region)
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Quick Overview for SHOX2 抗体 (Middle Region) (ABIN1109006)
抗原
See all SHOX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SEARVQVWFQ NRRAKCRKQE NQLHKGVLIG AASQFEACRV APYVNVGALR
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交叉反应 (详细)
- Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human
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纯化方法
- Purified using peptide immunoaffinity column
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免疫原
- The immunogen for anti-SHOX2 antibody: synthetic peptide directed towards the middle region of human SHOX2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- SHOX2 (Short Stature Homeobox 2 (SHOX2))
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别名
- SHOX2 / SHOT
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背景
- SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.Synonyms: Homeobox protein Og12X, OG12X, Paired-related homeobox protein SHOT, Short stature homeobox protein 2
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基因ID
- 6474
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NCBI登录号
- NP_006875
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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