SFTPD 抗体
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北京 101111
Quick Overview for SFTPD 抗体 (ABIN1108994)
抗原
See all SFTPD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Human, rat
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纯化方法
- Protein G
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亚型
- IgG1
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anti-Surfactant Protein D (SFTPD) (AA 301-375) antibody
SFTPD 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein D (SFTPD) (AA 259-374) antibodySFTPD 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein D (SFTPD) (AA 292-321), (C-Term) antibodySFTPD 适用: 人, 大鼠 WB, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein D (SFTPD) (AA 21-375) antibodySFTPD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein D (SFTPD) (AA 21-375) antibodySFTPD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Surfactant Protein D (SFTPD) antibodySFTPD 适用: Pig WB, IHC (p), IHC (fro), IF 宿主: 小鼠 Monoclonal 1-7 unconjugated
anti-Surfactant Protein D (SFTPD) (AA 21-375) antibodySFTPD 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-Surfactant Protein D (SFTPD) (AA 45-221) antibodySFTPD 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein D (SFTPD) (AA 50-64) antibodySFTPD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein D (SFTPD) (AA 21-375) antibodySFTPD 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- SFTPD (Surfactant Protein D (SFTPD))
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别名
- SFTPD
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背景
- SP-D belongs to the collectin familiy. These proteins are oligomeric proteins composed of carbohydrate-recognition domains (CRD) attached to collagenous regions. They are structurally similar to the ficolins although they make use of different CRD structures: C-type lectin domain for the collectins. The anti-microbial effector mechanisms of SP-D are direct opsonization, neutralization, and agglutination. Thus limiting the infection and concurrently orchestrating the subsequent adaptive immune response. The lung is the major site of synthesis of SP-D, where the molecules are produced and secreted onto the epithelial surface by alveolar type II cells and unciliated bronchial epithelial cells. SP-D is also found in different epithelial cells of the gastrointeststinal tract and in epithelial cells of exocrine glands. SP-D synthesis and secretion increase significantly after inflammatory stress. Increased amounts of SP-D in lavage and tissue, particularly in type II pneumocytes, in Clara cells and in hyperplastic goblet cells are found in inflamed lungs. The localization of SP-D in endocytic vesicles and in lysosomal granules of alveolar macrophages suggests that a receptor-mediated uptake occurs. SP-D binds to apoptotic neutrophils and enhances their clearance by alveolar macrophages.Synonyms: COLEC7, Collectin-7, Lung surfactant protein D, PSP-D, PSPD, Pulmonary surfactant-associated protein D, SFTP4, SP-D
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基因ID
- 10116
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UniProt
- P35248
抗原
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