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SFTPB 抗体

SFTPB 适用: 人, Pig, 小鼠, Cow WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1108992
发货至: 中国
  • 抗原 See all SFTPB 抗体
    SFTPB (Surfactant Protein B (SFTPB))
    适用
    • 27
    • 11
    • 10
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    人, Pig, 小鼠, Cow
    宿主
    • 36
    • 5
    克隆类型
    • 38
    • 3
    多克隆
    标记
    • 25
    • 7
    • 4
    • 3
    • 1
    • 1
    This SFTPB antibody is un-conjugated
    应用范围
    • 37
    • 20
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, bovine, pig
    纯化方法
    Protein A
    免疫原
    Human-based 60-amino acid synthetic SP-B polypeptide
    亚型
    IgG
    Top Product
    Discover our top product SFTPB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    SFTPB (Surfactant Protein B (SFTPB))
    别名
    SFTPB (SFTPB 产品)
    背景
    There are four surfactant-specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-B is synthesized by the alveolar type II epithelial cells as a 40-42 kD precursor that is subsequently proteolytically processed to 7.8-8 kD. SP-B enhances the spreading and stability of surfactant phospholipids in the alveolus. SP-B is essential for air-breathing in mammals and is therefore largely conserved. SP-B can interact with both phospholipid head groups and fatty chains and is particularly active in enhancing surface active behaviour in endogenous and exogenous lung surfactants. Even low SP-B contents had measurable effects in increasing the adsorption, dynamic surface tension lowering, and/or film respreading of DPPC, mixed synthetic lipids, and column-purified lung surfactant phospholipids. Deficiency of SP-B and other surfactant components is associated with respiratory distress syndrome (RDS) in premature infants and adults with respiratory distress syndrome (ARDS).Synonyms: 18 kDa pulmonary-surfactant protein, Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTP3, SP-B, Surfactant protein B
    基因ID
    9606
    UniProt
    P07988
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