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SFTPB 抗体

SFTPB 适用: 人, Pig WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1108991
发货至: 中国
  • 抗原 See all SFTPB 抗体
    SFTPB (Surfactant Protein B (SFTPB))
    适用
    • 31
    • 11
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    人, Pig
    宿主
    • 40
    • 5
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 25
    • 7
    • 5
    • 4
    • 2
    • 2
    This SFTPB antibody is un-conjugated
    应用范围
    • 41
    • 23
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes the surfactant protein B (SP-B). It rescognizes under nonreducing conditions the most prominent forms of SP-B of 8 kDa and 22 kDa, corresponding to SP-B dimers.
    交叉反应 (详细)
    Species reactivity (tested):Human, pig
    纯化方法
    Protein A
    免疫原
    Pig SP-B from pig lungs which has been reconstituted in micelles of lysophosphatidylcholine
    亚型
    IgG
    Top Product
    Discover our top product SFTPB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    SFTPB (Surfactant Protein B (SFTPB))
    别名
    SFTPB (SFTPB 产品)
    别名
    PSP-B antibody, SFTB3 antibody, SFTP3 antibody, SMDP1 antibody, SP-B antibody, AI562151 antibody, SF-B antibody, Sftp-3 antibody, Sftp3 antibody, Sp-b antibody, SFTPB antibody, sftpb antibody, xSP-B antibody, surfactant protein B antibody, surfactant associated protein B antibody, surfactant, pulmonary-associated protein B L homeolog antibody, SFTPB antibody, Sftpb antibody, sftpb.L antibody
    背景
    There are four surfactant-specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-B is synthesized by the alveolar type II epithelial cells as a 40-42 kD precursor that is subsequently proteolytically processed to 7.8-8 kD. SP-B enhances the spreading and stability of surfactant phospholipids in the alveolus. SP-B is essential for air-breathing in mammals and is therefore largely conserved. SP-B can interact with both phospholipid head groups and fatty chains and is particularly active in enhancing surface active behaviour in endogenous and exogenous lung surfactants. Even low SP-B contents had measurable effects in increasing the adsorption, dynamic surface tension lowering, and/or film respreading of DPPC, mixed synthetic lipids, and column-purified lung surfactant phospholipids. Deficiency of SP-B and other surfactant components is associated with respiratory distress syndrome (RDS) in premature infants and adults with respiratory distress syndrome (ARDS).Synonyms: 18 kDa pulmonary-surfactant protein, Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTP3, SP-B, Surfactant protein B
    基因ID
    6439
    NCBI登录号
    NP_000533
    UniProt
    P07988
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