SFTPB 抗体
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北京 101111
Quick Overview for SFTPB 抗体 (ABIN1108991)
抗原
See all SFTPB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes the surfactant protein B (SP-B). It rescognizes under nonreducing conditions the most prominent forms of SP-B of 8 kDa and 22 kDa, corresponding to SP-B dimers.
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交叉反应 （详细）
- Species reactivity (tested):Human, pig
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纯化方法
- Protein A
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免疫原
- Pig SP-B from pig lungs which has been reconstituted in micelles of lysophosphatidylcholine
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亚型
- IgG
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anti-Surfactant Protein B (SFTPB) (AA 111-352) antibody
SFTPB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein B (SFTPB) (AA 20-193) antibodySFTPB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein B (SFTPB) (AA 1-381) antibodySFTPB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein B (SFTPB) (AA 1-381) antibodySFTPB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H7 unconjugated
anti-Surfactant Protein B (SFTPB) (AA 194-243) antibodySFTPB 适用: 人, Pig, 大鼠, 犬, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein B (SFTPB) (AA 201-381) antibodySFTPB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein B (SFTPB) (Middle Region) antibodySFTPB 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein B (SFTPB) (Internal Region) antibodySFTPB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Surfactant Protein B (SFTPB) (AA 1-381) antibodySFTPB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- SFTPB (Surfactant Protein B (SFTPB))
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别名
- SFTPB
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背景
- There are four surfactant-specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-B is synthesized by the alveolar type II epithelial cells as a 40-42 kD precursor that is subsequently proteolytically processed to 7.8-8 kD. SP-B enhances the spreading and stability of surfactant phospholipids in the alveolus. SP-B is essential for air-breathing in mammals and is therefore largely conserved. SP-B can interact with both phospholipid head groups and fatty chains and is particularly active in enhancing surface active behaviour in endogenous and exogenous lung surfactants. Even low SP-B contents had measurable effects in increasing the adsorption, dynamic surface tension lowering, and/or film respreading of DPPC, mixed synthetic lipids, and column-purified lung surfactant phospholipids. Deficiency of SP-B and other surfactant components is associated with respiratory distress syndrome (RDS) in premature infants and adults with respiratory distress syndrome (ARDS).Synonyms: 18 kDa pulmonary-surfactant protein, Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTP3, SP-B, Surfactant protein B
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基因ID
- 6439
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NCBI登录号
- NP_000533
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UniProt
- P07988
抗原
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