AIMP1 抗体
Quick Overview for AIMP1 抗体 (ABIN1108957)
抗原
See all AIMP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Monoclonal antibody 546-2 reacts with endothelial-monocyte-activating polypeptide II (EMAP II), a 20 kDa polypeptide.
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交叉反应 （详细）
- Species reactivity (tested):Human, rat
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纯化方法
- Protein G
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亚型
- IgG2b
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anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 25-180) antibody
AIMP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 2-310) antibodyAIMP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 25-180) antibodyAIMP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (Internal Region) antibodyAIMP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) antibodyAIMP1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 137-149) antibodyVerified AIMP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 1-312) antibodyAIMP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C11 unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 1-312) antibodyAIMP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 1-312) antibodyAIMP1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal M1 unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) (AA 148-312) antibodyAIMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
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别名
- SCYE1 / EMAP2
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背景
- EMAP II is an antiangiogenic and proinflammatory cytokine (expressed by microglia/macrophages). EMAP II appears to be a profound modulator of inflammatory reactions of the innate immune system and might participate in a variety of pathogenic immune-processes in the mammalian brain. EMAP II is a potential mediator of inflammatory responses in autoimmunity and a considered target to stage reactions of monocytic lineage cells in inflammatory reactions. In normal tissues EMAP II is expressed in endocrine organs, in cells of neuroendocrine origin, but also in tissues with high cell turnover. Under pathophysiological conditions EMAP II has several functions. It triggers the recruitment of macrophages by elevating cytosolic-free Ca2+ concentrations, it stimulates leukocyte chemotaxis, it induces the expression of TNF-alpha and tissue factor (TF) by monocytes and myeloperoxidase (MPO) by polymorphonuclear cells (PNMs). Furthermore it stimulates the release of von Willebrand-factor, P- and E-selectin by endothelial cells and EMAP II induces endothelial programmed cell death in vitro.Synonyms: AIMP1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP-2, EMAP-II, Endothelial monocyte-activating polypeptide 2, Endothelial monocyte-activating polypeptide II, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1
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基因ID
- 9255
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NCBI登录号
- NP_001135887
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UniProt
- Q12904
抗原
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