SCARB1 抗体
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- 抗原 See all SCARB1 抗体
- SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SCARB1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- This antibody reacts with rat class B scavenger receptor type I (SR-BI). It blocks the biological activity of rat SR-BI. For example, it inhibits the ability of SR-BI to mediate the corporation of lipids of HDL by SR-BI expressing cells.
- 交叉反应 （详细）
- Species reactivity (tested):Rat
- 纯化方法
- Protein G
- 克隆位点
- SR-BI
- 亚型
- IgG1
- Top Product
- Discover our top product SCARB1 Primary Antibody
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anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 21-100) antibody
SCARB1 适用: 人, 大鼠, 小鼠, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 450-509), (C-Term) antibodySCARB1 适用: 人, 大鼠, 小鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 33-440) antibodySCARB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (Internal Region) antibodySCARB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 238-250) antibodyVerified SCARB1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) antibodySCARB1 WB, IF, IP, ICC, BP 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 450-509) antibodySCARB1 适用: 人, 大鼠, 小鼠, Hamster WB, IHC, IF, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 1-100) antibodySCARB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) antibodySCARB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 33-443) antibodySCARB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.1 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2 - 8 °C.
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- 抗原
- SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
- 别名
- SCARB1 (SCARB1 产品)
- 别名
- cb1015 antibody, SCARB1 antibody, Scarb1 antibody, CD36L1 antibody, CLA-1 antibody, CLA1 antibody, HDLQTL6 antibody, SR-BI antibody, SRB1 antibody, AI120173 antibody, CD36 antibody, Cd36l1 antibody, Cla-1 antibody, Cla1 antibody, D5Ertd460e antibody, Hdlq1 antibody, Hlb398 antibody, SR-B1 antibody, SRBI antibody, Srb1 antibody, mSR-BI antibody, scavenger receptor class B, member 1 antibody, scavenger receptor class B member 1 antibody, scarb1 antibody, SCARB1 antibody, Scarb1 antibody, CpipJ_CPIJ014332 antibody, CpipJ_CPIJ019101 antibody
- 背景
- Scavenger receptors have been studied primarily for their ability to bind and internalize modified lipoproteins. They have been found in the development of atherosclerosis and other macrophage-associated functions. Scavenger receptors also function as pattern recognition receptors for a wide variety of pathogens. This finding indicates a potential role in host defense. SR-BI belongs together with CD36 to the class B scavenger receptor family. SR-BI is a multiligand membrane protein existing in various organs such as the liver and various cell types such as endothelial cells, macrophages, brain cells, Leydig cells and Sertoli cells. SR-BI has been found as a receptor for phospholipids, free and (lipo)protein-bound ApoE, lipid-bound ApoA-I, HDL, hypochlorite-modified LDL and more. In liver, the PDZK-1 (and possible other PDZ domains) of SR-BI has been found to be essential for cell surface expression and, hence, reverse cholesterol transport. In the brain, the presence of SR-BI seems to be involved in the uptake of oxidatively modified lipoproteins and beta-amyloid protein complexed with ApoE, suggesting SR-BI to be an important tool for studies on neurodegenerative disorders. In the testis, SR-BI is expressed in two somatic cell types: Leydig cells and Sertoli cells. SR-BI functions at least partly as a phosphatidyl serine receptor (PSR), enabling Sertoli cells to recognize and phagocytose apoptotic spermatogenic cells at all stages of differentiation.Synonyms: CD36 and LIMPII analogous 1, CD36 antigen-like 1, CD36L1, CLA-1, CLA1, Collagen type I receptor thrombospondin receptor-like 1, SR-BI, SRB1, Scavenger receptor class B member 1
- 基因ID
- 25073
- NCBI登录号
- NP_113729
- UniProt
- P97943
- 途径
- Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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