SCARB1 抗体
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北京 101111
Quick Overview for SCARB1 抗体 (ABIN1108937)
抗原
See all SCARB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with rat class B scavenger receptor type I (SR-BI). It blocks the biological activity of rat SR-BI. For example, it inhibits the ability of SR-BI to mediate the corporation of lipids of HDL by SR-BI expressing cells.
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交叉反应 （详细）
- Species reactivity (tested):Rat
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纯化方法
- Protein G
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亚型
- IgG1
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anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 21-100) antibody
SCARB1 适用: 人, 大鼠, 小鼠, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 450-509), (C-Term) antibodySCARB1 适用: 人, 大鼠, 小鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 33-440) antibodySCARB1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (Internal Region) antibodySCARB1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 1-100) antibodySCARB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 238-250) antibodyVerified SCARB1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 33-443) antibodySCARB1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (C-Term) antibodyVerified SCARB1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) antibodyKD Validated SCARB1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1395 unconjugated Recombinant Antibody
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 114-163) antibodySCARB1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
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别名
- SCARB1
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背景
- Scavenger receptors have been studied primarily for their ability to bind and internalize modified lipoproteins. They have been found in the development of atherosclerosis and other macrophage-associated functions. Scavenger receptors also function as pattern recognition receptors for a wide variety of pathogens. This finding indicates a potential role in host defense. SR-BI belongs together with CD36 to the class B scavenger receptor family. SR-BI is a multiligand membrane protein existing in various organs such as the liver and various cell types such as endothelial cells, macrophages, brain cells, Leydig cells and Sertoli cells. SR-BI has been found as a receptor for phospholipids, free and (lipo)protein-bound ApoE, lipid-bound ApoA-I, HDL, hypochlorite-modified LDL and more. In liver, the PDZK-1 (and possible other PDZ domains) of SR-BI has been found to be essential for cell surface expression and, hence, reverse cholesterol transport. In the brain, the presence of SR-BI seems to be involved in the uptake of oxidatively modified lipoproteins and beta-amyloid protein complexed with ApoE, suggesting SR-BI to be an important tool for studies on neurodegenerative disorders. In the testis, SR-BI is expressed in two somatic cell types: Leydig cells and Sertoli cells. SR-BI functions at least partly as a phosphatidyl serine receptor (PSR), enabling Sertoli cells to recognize and phagocytose apoptotic spermatogenic cells at all stages of differentiation.Synonyms: CD36 and LIMPII analogous 1, CD36 antigen-like 1, CD36L1, CLA-1, CLA1, Collagen type I receptor thrombospondin receptor-like 1, SR-BI, SRB1, Scavenger receptor class B member 1
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基因ID
- 25073
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NCBI登录号
- NP_113729
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UniProt
- P97943
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途径
- Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
抗原
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