Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)
缓冲液
10 mM Ammonium Bicarbonate buffer, 2 mg BSA
注意事项
Be careful opening the vial since the antibody resides in a vacuum.
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C.
抗原
EXOSC2
(Exosome Component 2 (EXOSC2))
别名
RRP4 / EXOSC2
背景
The exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.Synonyms: Exosome complex exonuclease RRP4, Exosome component 2, Ribosomal RNA-processing protein 4