EXOSC2 抗体
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Quick Overview for EXOSC2 抗体 (ABIN1108908)
抗原
See all EXOSC2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specificity has been tested in ELISA. Additional tests for cross reactivity have not yet been performed.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Purified
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免疫原
- Recombinant GST-hRRP4 (NCBI accession number NM_014285 REGION 3-884, expression vector pGEX-4T3), expressed in E.coli.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)
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缓冲液
- 10 mM Ammonium Bicarbonate buffer, 2 mg BSA
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注意事项
- Be careful opening the vial since the antibody resides in a vacuum.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- EXOSC2 (Exosome Component 2 (EXOSC2))
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别名
- RRP4 / EXOSC2
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背景
- The exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.Synonyms: Exosome complex exonuclease RRP4, Exosome component 2, Ribosomal RNA-processing protein 4
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基因ID
- 23404
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NCBI登录号
- NP_055100
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UniProt
- Q13868
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途径
- SARS-CoV-2 Protein Interactome
抗原
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