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Reticulon 4 抗体 (C-Term, Isoform 1)

This anti-Reticulon 4 antibody is a 兔 多克隆 antibody detecting Reticulon 4 in WB, IHC (p), IP 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1108866
发货至: 中国

Quick Overview for Reticulon 4 抗体 (C-Term, Isoform 1) (ABIN1108866)

抗原

See all Reticulon 4 (RTN4) 抗体
Reticulon 4 (RTN4)

适用

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人, 小鼠, 大鼠

宿主

  • 75
  • 3
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  • 2
  • 2
  • 2

克隆类型

  • 70
  • 17
多克隆

标记

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  • 4
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  • 1
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This Reticulon 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 抗原表位

    • 16
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    • 1
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    C-Term, Isoform 1

    特异性

    This antibody detects Reticulon-4 / RTN4 Isoform 1 at C-term. No cross reactivity with other proteins.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Immunogen affinity purified

    免疫原

    Synthetic peptide corresponding to the C-terminal of human Nogo-A .Remarks: Sequence is identical to the related mouse sequence.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Reticulon 4 (RTN4)

    别名

    Reticulon-4 / RTN4

    背景

    Human neurite outgrowth inhibitor (NOGO) cDNAs encodes 3 splice variants: NOGOA, NOGOB and NOGOC. The longest cDNA, designated NOGOA, has an open reading frame of 1192 amino acids. It is a potent inhibitor of neurite growth and an IN-1 antigen produced by oligodendrocytes, and may allow the generation of new reagents to enhance CNS regeneration and plasticity. Nogo-A, a member of the Reticulon family, is expressed by oligodendrocytes and associates primarily with the endoplasmic reticulum. The acidic amino terminus of Nogo-A is detected at the cytosolic face of cellular membranes and may contribute to inhibition of axon regeneration at sites of oligodendrocyte injury. A multivalent form of the N terminus of Nogo-A affects the morphology of both neurons and other cell types.Synonyms: Foocen, KIAA0886, NOGO, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Reticulon-5

    基因ID

    57142

    NCBI登录号

    NP_065393

    UniProt

    Q9NQC3

    途径

    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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