RECK 抗体 (AA 621-832)
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Quick Overview for RECK 抗体 (AA 621-832) (ABIN1108847)
抗原
See all RECK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 621-832
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特异性
- This antibody reacts with RECK.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein A agarose
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免疫原
- Recombinant RECK protein (621-832 a.a)
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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别名
- RECK / ST15
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背景
- A membrane-anchored glycoprotein, RECK is encoded by a RECK gene (reversion-inducing cysteine-rich protein with Kazal motifs) identified as a transformation suppressor gene. This 110 kDa protein consists of 971a.a. The protein contains protease inhibitor like domains such as the Kazal motif, and epidermal growth factor (EGF) like repeats. Takahashi et al. reported that restoration pf RECK expression in malignant cells resulted in suppression of invasive activity with a concomitant decrease in the secretion of matrix metalloproteinase-9 (MMP-9), a key enzyme involved in tumor invasion and metastasis.Synonyms: Reversion-inducing cysteine-rich protein with Kazal motifs, Suppressor of tumorigenicity 15 protein
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基因ID
- 8434
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NCBI登录号
- NP_066934
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UniProt
- O95980
抗原
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