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PROC 抗体 (activated, Light Chain)

This anti-PROC antibody is a 大鼠单克隆 antibody detecting PROC in WB 和 EIA. Suitable for 人.

产品编号 ABIN1108749

发货至: 中国

Quick Overview for PROC 抗体 (activated, Light Chain) (ABIN1108749)

抗原

See all PROC 抗体

PROC (Vitamin K-dependent protein C (PROC))

适用

90
13
9
4
3
2
1
1
1
1

人

宿主

大鼠

克隆类型

单克隆

标记

70
6
5
4
3
2
2
2
2
2
2
2
1

This PROC antibody is un-conjugated

应用范围

63
46
30
20
15
15
10
7
6
6
6
3
3
2
2
2
2
1
1
1
1
1
1

Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

PC107

Discover our top product PROC Primary Antibody

抗原表位
7

5

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
activated, Light Chain

交叉反应（详细）

Species reactivity (tested):Human

纯化方法

Protein G

亚型

IgG1
anti-Vitamin K-dependent protein C (PROC) (AA 32-131) antibody
PROC 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A10 unconjugated

anti-Vitamin K-dependent protein C (PROC) antibody
PROC 适用: 人 ELISA, IHC, IHC (p), IEP 宿主: 山羊 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 446-461), (C-Term) antibody
PROC 适用: 人 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 1-236) antibody
PROC 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) antibody
PROC 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (Middle Region) antibody
PROC 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 197-436) antibody
PROC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 17-166) antibody
PROC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 288-409) antibody
PROC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) antibody
PROC 适用: 人 ELISA, Purif, BP 宿主: 小鼠 Monoclonal HPC-4 unconjugated Recombinant Antibody

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

0.1 mg/mL

缓冲液

PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store at 2 - 8 °C.
抗原

PROC (Vitamin K-dependent protein C (PROC))

别名

Protein C

背景

Protein C (PC) is an important regulator of the blood coagulation system. The anticoagulant PC is converted to activated protein C (APC) by the thrombomodulin (TM)-thrombin complex on the phospholipid surface of endothelial cells, monocytes, and platelets. This process is enhanced in the presence of the endothelial protein C receptor (EPCR). In addition to its regulatory function in the blood coagulation system, studies indicate important roles for APC in inflammatory processes. The administration of APC prevents lethal effects of Escherichia coli-associated sepsis in experimental animal models and appears effective for the treatment of patients with meningococcemia or acquired PC deficiency. Treatment with APC improves the clinical outcome of patients with sepsis. The anti-inflammatory activity of APC depends on its ability to suppress the secretion of cytokines as tumor necrosis factor-alpha by inflammatory cells, the activation and extravasation of leukocytes and the expression and function of adhesion molecules. APC may also suppress the expression of growth factors and members of nuclear factor-kB (NF-kB) family of transcription factors.Synonyms: APC

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