PMVK 抗体 (Middle Region)
Quick Overview for PMVK 抗体 (Middle Region) (ABIN1108679)
抗原
See all PMVK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody detects PMVK (mid region). No cross reactivity with other proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide corresponding to a sequence mapping at the middle region of Human PMVK .Remarks: Sequence is different from the related Mouse and Rat sequence by single amino acid.
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亚型
- IgG
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anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibody
PMVK 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibodyPMVK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibodyPMVK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) antibodyPMVK 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Phosphomevalonate Kinase (PMVK) antibodyPMVK 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 15-120) antibodyPMVK 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibodyPMVK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 135-151), (Middle Region) antibodyPMVK 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- 0.2 mg Na2HPO4, 0.9 mg NaCl, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PMVK (Phosphomevalonate Kinase (PMVK))
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别名
- PMVK
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背景
- PMVK (phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence (PTS-1), Ser-Arg-Leu, at the C terminus of the protein.Synonyms: HUMPMKI, PMKI, PMKase, Phosphomevalonate kinase
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基因ID
- 10654
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NCBI登录号
- NP_006547
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UniProt
- Q15126
抗原
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