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PLVAP 抗体 (FITC)

PLVAP 适用: 人 WB, IHC (fro), IF 宿主: 小鼠 Monoclonal 174-2 FITC
产品编号 ABIN1108673
发货至: 中国
  • 抗原 See all PLVAP 抗体
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    适用
    • 27
    • 7
    • 1
    宿主
    • 21
    • 6
    • 5
    小鼠
    克隆类型
    • 22
    • 9
    单克隆
    标记
    • 19
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    This PLVAP antibody is conjugated to FITC
    应用范围
    • 29
    • 22
    • 16
    • 9
    • 6
    • 4
    • 4
    • 4
    • 1
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    克隆位点
    174-2
    亚型
    IgG1
    Top Product
    Discover our top product PLVAP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    别名
    PLVAP (PLVAP 产品)
    别名
    MECA32 antibody, Pv1 antibody, FELS antibody, PV-1 antibody, PV1 antibody, gp68 antibody, plasmalemma vesicle associated protein antibody, Plvap antibody, PLVAP antibody
    背景
    PLVAP is a 60 kDa type II transmembrane glycoprotein which tends to form homodimers. PLVAP is widely expressed in the vasculature of normal tissues. The vascular staining pattern of PLVAP is quite unique among the endothelial cell antigens, since expression of other antigens (like ICAM-1, P-selectin, E-selectin or VCAM-1) is not limited to vascular endothelial cells. PLVAP expression in the vascular endothelial cells of the CNS is lost in association with formation of an intact blood-brain barrier. However, in the endothelium of human brain tumors expression of PLVAP is specifically up-regulated, making it a suitable antiangiogenic target for brain tumor therapy and cerebral edema. Furthermore, PLVAP is expressed in the vasculature of most other human tumors and as such useful as marker for tumor angiogenesis.Synonyms: Endothelial Cell Antigen, Endothelial cell marker, Endothelial cell surface marker, FELS, Fenestrated endothelial-linked structure protein, MECA-32 antigen, PV-1, PV1, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein
    UniProt
    Q9BX97
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