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PIK3R1 抗体

PI3K p85a 适用: 人, 小鼠, 大鼠 WB, IF, IP 宿主: 小鼠 Monoclonal AB6 unconjugated
产品编号 ABIN1108652
发货至: 中国
  • 抗原 See all PIK3R1 (PI3K p85a) 抗体
    PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
    适用
    • 128
    • 95
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    • 18
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    • 7
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    人, 小鼠, 大鼠
    宿主
    • 114
    • 30
    小鼠
    克隆类型
    • 104
    • 40
    单克隆
    标记
    • 72
    • 11
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    • 5
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    This PIK3R1 antibody is un-conjugated
    应用范围
    • 116
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    • 28
    • 22
    • 17
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    • 12
    • 6
    • 4
    • 2
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    This antibody reacts with p85alpha, which is regulatory subunit of PI3-kinase on Western blot, Immunoprecipitation and Immunocytochemistry. This antibody recognizes mutant p85alpha protein expressed in E. coli to be possessed in amino acid position '1-79' described below. This antibody does not react with p85beta.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Protein A agarose
    免疫原
    Recombinant human p85alpha.
    克隆位点
    AB6
    亚型
    IgG1
    Top Product
    Discover our top product PI3K p85a Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
    别名
    PIK3R1 / GRB1 (PI3K p85a 产品)
    别名
    PI3CG antibody, PI3K antibody, PI3Kgamma antibody, PIK3 antibody, AGM7 antibody, GRB1 antibody, p85 antibody, p85-ALPHA antibody, PI3KA antibody, AA414921 antibody, C530050K14 antibody, p50alpha antibody, p55alpha antibody, p85alpha antibody, wu:fb65b05 antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma antibody, phosphoinositide-3-kinase regulatory subunit 1 antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta antibody, phosphoinositide-3-kinase, regulatory subunit 1 (alpha) antibody, PIK3CG antibody, PIK3R1 antibody, Pik3r1 antibody, Pik3cb antibody, pik3r1 antibody
    背景
    Phosphoinositide 3-kinase (PI3K) family of enzymes generate 3-phosphorylated phosphoinositides that act as second messengers downstream of numerous cellular receptors. This family control several cellular responses including cell growth, survival cytoskeletal remodeling and the trafficking of intracellular organelles in many different cell types. There are four subgroups (class IA, IB, II, III) of PI3K with distinct structure and substrate specificity. Class IA PI3K, which function downstream of activated tyrosine kinases, are heterodimers composed of a p110 catalytic subunit (a, b, or o) and a tightly associated regulatory subunit (p85a, p55a, p50a, p85B, or p55y). Each regulatory subunit can interchangeably associate with different catalytic subunits and shows a unique tissue distribution. p85a is the major regulatory subunit of class IA PI3Ks in most types of cells including immune cells.Synonyms: PI3-kinase subunit p85-alpha, PI3K regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha
    基因ID
    5295
    NCBI登录号
    NP_852556
    UniProt
    P27986
    途径
    TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect
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