PAX6 抗体 (Internal Region)
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Quick Overview for PAX6 抗体 (Internal Region) (ABIN1108593)
抗原
See all PAX6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Reacts with the Human 95 kDa PAX6 protein. Cross react with Mouse, Rat, Chicken, Zebrafish, Xenopus laevis and other species due to sequence homology.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat, Xenopus, Zebrafish.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Synthetic peptide derived from internal part of Human PAX6 protein
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore in distilled water.
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缓冲液
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PAX6 (Paired Box 6 (PAX6))
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别名
- PAX6
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背景
- PAX6 is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. PAX6 is required for the differentiation of pancreatic islet alpha cells and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. The Pax6-5A isoform appears to function as a molecular switch that specifies target genes.Synonyms: AN2, Aniridia type II protein, Oculorhombin, Paired box protein Pax-6, Pax-6
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基因ID
- 5080
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NCBI登录号
- NP_000271
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途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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