PARP4 抗体 (AA 408-611)
Quick Overview for PARP4 抗体 (AA 408-611) (ABIN1108587)
抗原
See all PARP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 408-611
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特异性
- This Monoclonal antobofdy P193-6 reacts with an internal epitope (amino acids 593-599, FSKVEDY) of the minor vault protein (p193 or VPARP), which is overexpressed in various Human non-P-glycoprotein MDR tumor cell lines, accordingly to an increase in the number of vault particles.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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免疫原
- E. coli lysate transformed with the pET28a(+) expression vector containing amino acids 408-611 of the p193 cDNA.
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亚型
- IgG2b
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anti-Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4) (AA 338-609) antibody
PARP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4) antibodyPARP4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4) (Internal Region) antibodyPARP4 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4) (AA 31-140) antibodyPARP4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4) (AA 1-300) antibodyPARP4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg IgG/ml
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缓冲液
- 0.09 % Sodium Azide 9 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PARP4 (Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4))
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别名
- PARP4
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背景
- PARP-1 is a nuclear protein that is specifically cleaved by caspase-3 and caspase-6, but not by caspase-1, into a signature apoptotic fragment. PARP-2 and PARP-3 interact with PARP-1. PARP-4, also designated vault poly(ADP-ribose) polymerase (VPARP) and ADP-ribotransferase-like 1 (ADPRTL1), associates with the major vault protein (MVP) and telomerase-associated protein 1 (TEP1) to form vaults, barrel-shaped cytoplasmic ribonucleoprotein particles. PARP-4 localizes mainly to the cytoplasm but is also found in the nucleus. The PARP-4 protein is expressed widely, with highest levels observed in the kidney, and is also detected in skeletal muscle, heart, leukocytes, placenta, lung, liver, spleen, and pancreas. PARP-4 contains a PARP (ADPRT)-like catalytic domain, a C-terminal MVP-interacting domain, a domain with two sequences similar to inter-alpha-trypsin inhibitor, and an N-terminal BRCA1 C-terminus (BRCT) domain, which may be involved in protein-protein interactions.Synonyms: 193 kDa vault protein, ADPRTL1, KIAA0177, PARP-4, PARP-related/IalphaI-related H5/proline-rich, PARPL, Poly [ADP-ribose] polymerase 4, VPARP, Vault poly(ADP-ribose) polymerase
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基因ID
- 143
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NCBI登录号
- NP_006428
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UniProt
- Q9UKK3
抗原
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