PNPLA6 抗体 (C-Term)
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Quick Overview for PNPLA6 抗体 (C-Term) (ABIN1108496)
抗原
See all PNPLA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1323-1348, C-Term
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特异性
- This antibody detects NTE at aa 1323-1348. No cross reactivity with other proteins.
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交叉反应 (详细)
- Species reactivity (tested):Zebrafish
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纯化方法
- Immunogen affinity purified
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免疫原
- Synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6 (1323-1348 amino acid)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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别名
- NTE
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背景
- Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging.Synonyms: Neuropathy target esterase, PNPLA6
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基因ID
- 10908
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NCBI登录号
- NP_006693
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UniProt
- Q8IY17
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途径
- Ribonucleoside Biosynthetic Process
抗原
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