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NOS1 抗体 (N-Term)

NOS1 适用: 人, 大鼠, 山羊, Pig WB 宿主: 小鼠 Monoclonal N1 unconjugated
产品编号 ABIN1108474
发货至: 中国
  • 抗原 See all NOS1 抗体
    NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
    抗原表位
    • 27
    • 15
    • 12
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-181, N-Term
    适用
    • 124
    • 88
    • 62
    • 15
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 山羊, Pig
    宿主
    • 133
    • 18
    • 3
    小鼠
    克隆类型
    • 128
    • 26
    单克隆
    标记
    • 67
    • 20
    • 11
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This NOS1 antibody is un-conjugated
    应用范围
    • 114
    • 61
    • 46
    • 29
    • 27
    • 27
    • 26
    • 20
    • 18
    • 12
    • 8
    • 6
    • 5
    • 4
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to NOS1 (1-181).
    纯化方法
    Affinity chromatography
    免疫原
    Protein A fusion protein
    克隆位点
    N1
    亚型
    IgG1
    Top Product
    Discover our top product NOS1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.2 % sodium acetate or neutral PBS
    浓度
    0,1 mg/mL
    缓冲液
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
    别名
    NOS1 (NOS1 产品)
    别名
    NOS1 antibody, IHPS1 antibody, N-NOS antibody, NC-NOS antibody, NOS antibody, bNOS antibody, nNOS antibody, 2310005C01Rik antibody, NO antibody, NOS-I antibody, Nos-1 antibody, nos antibody, ihps1 antibody, nnos antibody, nos1 antibody, nos1-A antibody, nanos C2HC-type zinc finger 1 antibody, nitric oxide synthase 1 antibody, nitric oxide synthase 1, neuronal antibody, nitric oxide synthase 1 (neuronal) antibody, nitric oxide synthase 1 L homeolog antibody, NANOS1 antibody, NOS1 antibody, Nos1 antibody, nos1 antibody, nos1.L antibody
    背景
    Nitric Oxide Synthase 1(NOS1,neuronal NOS,nNOS1) is a messenger molecule, mediating the effect ofendothelium-derived relaxing factor in blood vessels and the cytotoxic actions of macrophages, and playing a part in neuronal communication in the brain. It may be involved in neuronal cell death and damage in neurological illness. nNOS1 localized to the 12q24.2 region of human chromosome 12. It splice variant, expressed in testis, that encodes an NH2-terminal truncated protein of 1098 amino acids. nNOS cDNA clones were shown to contain different 5' terminal exons spliced to a common exon 2.Genomic cloning and sequence analysis demonstrate that the unique exons are positioned within 300 bp of each other but separated from exon 2 by an intron that is at least 20 kb in length. The neuronal isoform of nitric oxide synthase is highly expressed in mammalian skeletal muscle, it suggested a specific role for NOS1 in the local metabolic inhibition of alpha-adrenergic vasoconstriction in active skeletal muscle. The novel gaseous neuromediator nitric oxide is thought to play an important role in development and plasticity. Despite this, gene-knockout mice lacking neuronal (Type I) nitric oxide synthase exhibit relatively normal brain development and behavior.Synonyms: Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, Nitric Oxide Synthase, bNOS, nNOS
    基因ID
    4842
    NCBI登录号
    NP_000611
    UniProt
    P29475
    途径
    Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
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