GRIN2B 抗体 (N-Term)
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Quick Overview for GRIN2B 抗体 (N-Term) (ABIN1108473)
抗原
See all GRIN2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects NMDAR2B at N-term. No cross reactivity with other proteins.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Immunogen affinity purified
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免疫原
- Peptide mapping at the N-terminus of NMDAR2B of human origin .Remarks: Sequence is identical to the related mouse sequence.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 1.2 % sodium acetate or neutral PBS. If 0.5 mL of PBS is used, the antibody concentration will be 100 μg/mL.
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浓度
- 100 ug/ml.
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缓冲液
- 50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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别名
- NMDAR2B
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背景
- The N-methyl-D-aspartate receptor 2B, also names as GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98 % and 96 % identical to the sequences of the rat and mouse Nmdar2b proteins, respectively. Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B (NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.Synonyms: GRIN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDA Receptor 2B
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基因ID
- 2904
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NCBI登录号
- NP_000825
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UniProt
- Q13224
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途径
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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