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MBP 抗体 (C-Term)

This anti-MBP antibody is a 兔 多克隆 antibody detecting MBP in WB, IP, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1108333
发货至: 中国

Quick Overview for MBP 抗体 (C-Term) (ABIN1108333)

抗原

See all MBP 抗体
MBP (Myelin Basic Protein (MBP))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

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多克隆

标记

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This MBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects Myelin Basic Protein at C-term. No cross reactivity with other proteins.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Immunogen affinity purified

    免疫原

    Synthetic peptide corresponding to a sequence at the C-terminal of the human MBP .Remarks: Sequence is identical to the related rat and mouse sequence.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    1.2 % sodium acetate or neutral PBS. If 0.5 mL of PBS is used, the antibody concentration will be 100 μg/mL.

    缓冲液

    50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MBP (Myelin Basic Protein (MBP))

    别名

    Myelin Basic Protein

    背景

    Myelin basic protein (MBP) is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the central nervous system and the peripheral nervous system, respectively. It is most abundant in hemopoietic system and contains seven exons distributed over 32-34 kb. MBP isolated from MS brain may differ in charge microheterogeneity which would affect antigenic determinants. MBP is mapped to chromosome 18q22-23. Failure in this gene expression would be correlated in the central white matter with extrapyramidal system degeneration signs. Moreover, it is a candidate autoantigen in the disease multiple sclerosis.Synonyms: MBP, Myelin membrane encephalitogenic protein

    基因ID

    4155

    NCBI登录号

    NP_001020252

    UniProt

    P02686
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