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MUC6 抗体

MUC6 适用: 人 IF, WB, IHC (p) 宿主: 小鼠 Monoclonal MG-31 unconjugated
产品编号 ABIN1108322
发货至: 中国
  • 抗原 See all MUC6 抗体
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    适用
    • 50
    • 4
    • 1
    宿主
    • 29
    • 21
    小鼠
    克隆类型
    • 34
    • 16
    单克隆
    标记
    • 23
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    This MUC6 antibody is un-conjugated
    应用范围
    • 22
    • 20
    • 19
    • 17
    • 16
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts to Mucin-6.
    纯化方法
    Affinity chromatography
    免疫原
    Mucin from human ovarian cyst fluid
    克隆位点
    MG-31
    亚型
    IgG1
    Top Product
    Discover our top product MUC6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore in 1.2 % sodium acetate or neutral PBS
    浓度
    0,1 mg/mL
    缓冲液
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    别名
    Mucin-6 (MUC6 产品)
    别名
    gastric antibody, MUC-6 antibody, mucin-6-like antibody, mucin 6, oligomeric mucus/gel-forming antibody, mucin 6, gastric antibody, LOC100850574 antibody, MUC6 antibody, Muc6 antibody
    背景
    MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90 % breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Mucin gastric 6 (MUC6) is a large glycoprotein thought to play a major role in protecting the gastrointestinal tract from acid, proteases, pathogenic microorganisms and mechanical trauma. Expression of the gene was highest in the stomach and gallbladder, with weaker expression in the terminal ileum and right colon. Mucin glycoproteins play a key role in the normal function of the epithelium lining the gastrointestinal tract.Synonyms: Gastric mucin-6, MUC-6, MUC6
    基因ID
    4588
    NCBI登录号
    NP_005952
    UniProt
    Q6W4X9
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