MUC6 抗体
Quick Overview for MUC6 抗体 (ABIN1108322)
抗原
See all MUC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to Mucin-6.
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纯化方法
- Affinity chromatography
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免疫原
- Mucin from human ovarian cyst fluid
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亚型
- IgG1
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anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) (AA 2338-2439) antibody
MUC6 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, StM 宿主: 兔 Monoclonal MUC6-1553R unconjugated Recombinant Antibody
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-806R unconjugated Recombinant Antibody
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MUC6-916 unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal CLH5 unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) (AA 2338-2439) antibody (Biotin)MUC6 适用: 人 WB 宿主: 兔 Polyclonal Biotin
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) (C-Term) antibodyMUC6 适用: 人, 小鼠 IF, WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IF, WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal MUC6-916 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore in 1.2 % sodium acetate or neutral PBS
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浓度
- 0,1 mg/mL
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缓冲液
- 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
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别名
- Mucin-6
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背景
- MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90 % breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Mucin gastric 6 (MUC6) is a large glycoprotein thought to play a major role in protecting the gastrointestinal tract from acid, proteases, pathogenic microorganisms and mechanical trauma. Expression of the gene was highest in the stomach and gallbladder, with weaker expression in the terminal ileum and right colon. Mucin glycoproteins play a key role in the normal function of the epithelium lining the gastrointestinal tract.Synonyms: Gastric mucin-6, MUC-6, MUC6
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基因ID
- 4588
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NCBI登录号
- NP_005952
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UniProt
- Q6W4X9
抗原
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