Methylglyoxal Modified Proteins 抗体
The 小鼠 单克隆 anti-Methylglyoxal Modified Proteins antibody (Clone MGO-1) (ABIN1108230) specifically detects Methylglyoxal Modified Proteins in IHC (p), WB 和 EIA.
The antibody is reactive with Various Species samples.
产品编号 ABIN1108230
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Methylglyoxal Modified Proteins 抗体 (ABIN1108230)
抗原
Methylglyoxal Modified Proteins
适用
Various Species
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Enzyme Immunoassay (EIA)
克隆位点
MGO-1
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交叉反应 （详细）
- Species reactivity (tested):Human. Multispecies cross reactant.
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纯化方法
- Protein G
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免疫原
- MGO-modified KLH
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- Methylglyoxal Modified Proteins
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背景
- Methylglyoxal (MGO) is an endogenous product of glucose metabolism. Increased production and accumulation of methylglyoxal (MGO), as well as increased modification of proteins by glycoxidation, are hallmarks of aging and diabetes. MGO was shown to modify proteins and to contribute to the accumulation of damaged proteins that can be toxic to cells. A number of studies have shown that MGO levels are significantly elevated in patients with Type 2 Diabetes and correlates well with fasting plasma glucose and hemoglobin A1c (HbA1c) levels. Moreover, increased formation of the MGO is implicated in renal dysfunction and is known to be involved in the development of DN (diabetic nephropathy).
抗原
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