MATK 抗体
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北京 101111
Quick Overview for MATK 抗体 (ABIN1108164)
抗原
See all MATK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to MATK.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein G
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 0,03'% sodium azide, 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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别名
- MATK
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背景
- MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.Synonyms: CHK, CTK, HYL, HYLTK, Hematopoietic consensus tyrosine-lacking kinase, Megakaryocyte-associated tyrosine-protein kinase
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分子量
- 56 kDa
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基因ID
- 4145
抗原
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