MAMLD1 抗体 (N-Term)
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Quick Overview for MAMLD1 抗体 (N-Term) (ABIN1108113)
抗原
See all MAMLD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LEELTKIQDP SPNELDLEKI LGTKPEEPLV LDHPQATLST TPKPSVQMSH
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交叉反应 (详细)
- Species reactivity (expected):Mouse, African clawed frog, DogSpecies reactivity (tested):Human
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纯化方法
- Purified using Protein A affinity column
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免疫原
- The immunogen for anti-CXORF6 antibody: synthetic peptide directed towards the N terminal of human CXORF6
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 100 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))
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别名
- MAMLD1
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背景
- Mastermind-like domain-containing protein 1 or CXorf6 transactivates the HES3 promoter independently of NOTCH proteins. HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ. MAMLD1 is expressed in fetal brain, fetal ovary, fetal testis, adult brain, ovary, skin, testis, uterus and highly expressed in skeletal muscle. Defects in MAMLD1 are a cause of X-linked hypospadias type 2 (HYSP2). Hypospadias is a common malformation in which the urethra opens on the ventral side of the penis. It is considered a complex disorder with both genetic and environmental factors involved in the pathogenesis. Hypospadias can occur alone on an apparently multifactorial basis or as part of syndromes.Mastermind-like domain-containing protein 1Synonyms: CXorf6, F18, Mastermind-like domain-containing protein 1, Protein CG1
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基因ID
- 10046
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NCBI登录号
- NP_005482
抗原
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