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MAMLD1 抗体 (N-Term)

This anti-MAMLD1 antibody is a 兔 多克隆 antibody detecting MAMLD1 in WB. Suitable for 人, 犬, 小鼠 和 非洲爪蟾.
产品编号 ABIN1108113
发货至: 中国

Quick Overview for MAMLD1 抗体 (N-Term) (ABIN1108113)

抗原

See all MAMLD1 抗体
MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))

适用

  • 7
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 犬, 小鼠, 非洲爪蟾

宿主

  • 5
  • 2

克隆类型

  • 6
  • 1
多克隆

标记

  • 7
This MAMLD1 antibody is un-conjugated

应用范围

  • 7
  • 3
Western Blotting (WB)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    N-Term

    序列

    LEELTKIQDP SPNELDLEKI LGTKPEEPLV LDHPQATLST TPKPSVQMSH

    交叉反应 (详细)

    Species reactivity (expected):Mouse, African clawed frog, DogSpecies reactivity (tested):Human

    纯化方法

    Purified using Protein A affinity column

    免疫原

    The immunogen for anti-CXORF6 antibody: synthetic peptide directed towards the N terminal of human CXORF6
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Add 100 μL of distilled water to a final concentration of 1 mg/mL.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原

    MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))

    别名

    MAMLD1

    背景

    Mastermind-like domain-containing protein 1 or CXorf6 transactivates the HES3 promoter independently of NOTCH proteins. HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ. MAMLD1 is expressed in fetal brain, fetal ovary, fetal testis, adult brain, ovary, skin, testis, uterus and highly expressed in skeletal muscle. Defects in MAMLD1 are a cause of X-linked hypospadias type 2 (HYSP2). Hypospadias is a common malformation in which the urethra opens on the ventral side of the penis. It is considered a complex disorder with both genetic and environmental factors involved in the pathogenesis. Hypospadias can occur alone on an apparently multifactorial basis or as part of syndromes.Mastermind-like domain-containing protein 1Synonyms: CXorf6, F18, Mastermind-like domain-containing protein 1, Protein CG1

    基因ID

    10046

    NCBI登录号

    NP_005482
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