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Endothelin 1 抗体 (C-Term)

This anti-Endothelin 1 antibody is a 大鼠 单克隆 antibody detecting Endothelin 1 in RIA 和 IHC (fro). Suitable for 人.
产品编号 ABIN110809
发货至: 中国

Quick Overview for Endothelin 1 抗体 (C-Term) (ABIN110809)

抗原

See all Endothelin 1 (EDN1) 抗体
Endothelin 1 (EDN1)

适用

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  • 2
  • 1
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宿主

  • 108
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  • 1
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大鼠

克隆类型

  • 111
  • 46
单克隆

标记

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  • 2
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  • 2
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  • 1
  • 1
  • 1
  • 1
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  • 1
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This Endothelin 1 antibody is un-conjugated

应用范围

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Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

3G10
  • 抗原表位

    • 15
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    C-Term

    序列

    C-H-L-D-I-I-W

    特异性

    Reacts with the C-terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin.

    纯化方法

    Protein G affinity chromatography

    免疫原

    Synthetic human endothelin-C terminal fragment, conjugated to BSA

    亚型

    IgG2b
  • 应用备注

    RIA / IRMA. Immunohistochemistry on frozen sections: Frozen sections processed with dry acetone are recommended. Paraformaldehyde is notrecommended as it destroys the epitope.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Endothelin 1 (EDN1)

    别名

    Endothelin-1

    背景

    Endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.Synonyms: Big endothelin-1, EDN1, EDN2, ET-2, ET-3, Endothelin-2, Endothelin1, PPET1, PPET2, PPET3, Preproendothelin-1, Preproendothelin-2, Preproendothelin-3

    基因ID

    1906

    NCBI登录号

    NP_001946

    UniProt

    P05305

    途径

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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