LRG1 抗体
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北京 101111
Quick Overview for LRG1 抗体 (ABIN1108060)
抗原
See all LRG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody recognizes leucine-rich alpha-2-glycoprotein (LRG), a member of the leucine-rich repeat family. It can be used for immuno purification of human LRG.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein G
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免疫原
- Human LRG, covalently coupled to hemocyanin using glutaraldehyde
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))
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别名
- LRG1
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背景
- LRG is a plasma protein of approximately 50 kDa. LRG consists of 312 amino acids. It has 1 galactosamine and 4 glucosamine oliogosacharides attached and has 2 intrachain disulfide bonds. Leucine comprises 66 of the 312 amino acids, and LRG contains at least eight 24-amino acid leucine-rich repeats. The consensus of these residues, termed leucine-rich repeats (LRR), has been identified as an LRR-containing domain. The primary function of LRRs is to provide versatile structural framework of the formation of protein-protein interactions. LRG is expressed during granulocyte differentiation. Although several family members of the leucine-rich repeat family have been shown to be involved in signal transduction, protein-protein interaction, or cell adhesion and development, a function for LRG remains elusive. LRG has been reported as a biomarker for certain diseases including microbial infections and cancer. LRG can be detected in human neutrophils and progenitor cells, but not in peripheral blood mononuclear cells.Synonyms: LRG, Leucine-rich alpha-2-glycoprotein
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基因ID
- 116844
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NCBI登录号
- NP_443204
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UniProt
- P02750
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途径
- Brown Fat Cell Differentiation
抗原
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