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Lactoferrin 抗体

This anti-Lactoferrin antibody is a 牛 多克隆 antibody detecting Lactoferrin in WB, IP 和 EIA. Suitable for 人.
产品编号 ABIN1107999
发货至: 中国

Quick Overview for Lactoferrin 抗体 (ABIN1107999)

抗原

See all Lactoferrin (LTF) 抗体
Lactoferrin (LTF) (Lactotransferrin (LTF))

适用

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宿主

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克隆类型

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多克隆

标记

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This Lactoferrin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
  • 交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2 - 8 °C.
  • 抗原

    Lactoferrin (LTF) (Lactotransferrin (LTF))

    别名

    Lactotransferrin

    背景

    Human lactoferrin (LF) is an 80 kDa glycoprotein which was first isolated from human milk. It plays an important part in the immune system and helps to fight infections. Lactoferrin promotes the health of the gastro-intestinal system by improving the intestinal microbial balance. In addition, LF can be found in epithelia and most body fluids and secretions. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration also represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation. Lactoferrin strongly binds to iron and this iron binding property is considered to be an important antimicrobial. Human lactoferrin binds to bacterial products through its highly positively charged N-terminus, it kills various bacteria, most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Cleavage by pepsin of lactoferrin leads to the release of lactoferricin H. This 47 amino acid peptide has more antimicrobial activity than its precursor and it can inhibit the classical but not the alternative complement pathway. Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

    基因ID

    9606

    UniProt

    P02788

    途径

    Transition Metal Ion Homeostasis
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