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JAM3 抗体

This 大鼠 单克隆 anti-JAM3 antibody (Clone 19H36) specifically detects JAM3 in IP, IHC (fro) 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1107891
发货至: 中国
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Quick Overview for JAM3 抗体 (ABIN1107891)

抗原

See all JAM3 抗体
JAM3 (Junctional Adhesion Molecule 3 (JAM3))

适用

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人, 小鼠

宿主

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大鼠

克隆类型

  • 40
  • 16
单克隆

标记

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This JAM3 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

19H36
  • 交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Protein G

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2 - 8 °C.
  • 抗原

    JAM3 (Junctional Adhesion Molecule 3 (JAM3))

    别名

    JAM3 / JAM-C

    背景

    Junctional adhesion molecule-C (JAM-C) also known as JAM-2 is a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the vascular endothelium, in particular of high endothelial venules (HEV). In adult murine tissue JAM-C expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.Synonyms: Junctional adhesion molecule 3, Junctional adhesion molecule C

    基因ID

    83964

    NCBI登录号

    NP_075766

    UniProt

    Q9D8B7
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