IL27 抗体 (FITC)
Quick Overview for IL27 抗体 (FITC) (ABIN1107838)
抗原
See all IL27 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes both natural and recombinant Human IL-27
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ion Exchange Chromatography.
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免疫原
- Recombinant Human IL-27.
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亚型
- IgG2a
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anti-Interleukin-27 Subunit alpha (IL27) antibody
IL27 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (AA 1-173) antibodyIL27 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (AA 29-234) antibodyIL27 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (AA 32-234) antibodyIL27 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (N-Term) antibodyIL27 适用: 人, 小鼠 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-27 Subunit alpha (IL27) (AA 29-234) antibodyIL27 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 5 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IL27 (Interleukin-27 Subunit alpha (IL27))
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别名
- Interleukin-27 / IL27A
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背景
- Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
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基因ID
- 246778
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NCBI登录号
- NP_663634
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UniProt
- Q8NEV9
抗原
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