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IL-2 抗体 (PE)

This anti-IL-2 antibody is a 小鼠 单克隆 antibody detecting IL-2 in FACS. Suitable for 人.
产品编号 ABIN1107823
发货至: 中国

Quick Overview for IL-2 抗体 (PE) (ABIN1107823)

抗原

See all IL-2 (IL2) 抗体
IL-2 (IL2) (Interleukin 2 (IL2))

适用

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小鼠

克隆类型

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单克隆

标记

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This IL-2 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

N7-48A
  • 特异性

    The antibody detects human Interleukin 2, which is a 15 kDa molecular weight glycoprotein. Other species not tested.

    纯化方法

    Affinity chromatography

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    Interleukin-2 / IL2

    背景

    The immune system reacts to a pathogen by activation of balanced network of the humoral and cellular immune responses. Subsequently the activated condition of the immune system will, after the elimination of the pathogen, be down-regulated to a balanced situation again. Control of the immune response requires efficient communication between the different cells involved in this response. This interaction is provided by cell/cell contact and by a complex array of mediators. Among these mediators cytokines, soluble factors produced by these cells, play an important role. Cytokines can act on other cells locally or distantly, but can be even auto regulating. Cytokines can behave stimulatory or inhibitory, or can even perform both activities, depending on the (pre)activation stage of the target cell. (3, 4) Interleukine 2 (IL-2) is a cytokine expressed by human lymphocytes that have been stimulated by antigens or mitogens. Without stimulation, IL-2 is produced in low amounts by TH1 cells in vivo. Originally, IL-2 was referred to as T cell growth factor. T cell hybridomas or a leukemia cell line such as Jurkat, produce increased amounts of IL-2 in vitro. Stimulation with IL-2 leads to rapid clonal expansion of T cells and IL-2 acts on a variety of cells in vivo, such as B cells, NK cells, monocytes and macrophages. Furthermore, IL-2 can induce activation of LAK cells.Synonyms: IL-2, T-cell growth factor, TCGF

    基因ID

    3558

    NCBI登录号

    NP_000577

    UniProt

    P60568

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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