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IL12B 抗体

IL12B 适用: 人, 绵羊, Cow WB, FACS, EIA, Func, ELISpot 宿主: 小鼠 Monoclonal CC301 unconjugated
产品编号 ABIN1107794
发货至: 中国
  • 抗原 See all IL12B 抗体
    IL12B (Interleukin 12 beta (IL12B))
    适用
    • 63
    • 41
    • 11
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 绵羊, Cow
    宿主
    • 80
    • 19
    • 3
    • 2
    小鼠
    克隆类型
    • 83
    • 21
    单克隆
    标记
    • 61
    • 9
    • 9
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL12B antibody is un-conjugated
    应用范围
    • 86
    • 58
    • 35
    • 16
    • 13
    • 13
    • 13
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Functional Studies (Func), ELISpot
    特异性
    This antibody recognises the p40 subunit of Bovine Interleukin-12, and binds to both the free subunit and the intact heterodimer.
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    内毒素水平
    < 0.01 EU/μg
    克隆位点
    CC301
    亚型
    IgG2a
    Top Product
    Discover our top product IL12B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, None, None
  • 抗原
    IL12B (Interleukin 12 beta (IL12B))
    别名
    Interleukin-12 beta / IL12B (IL12B 产品)
    别名
    CLMF antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12 antibody, IL-12 p40 antibody, il12b antibody, il12p40.b antibody, zgc:152789 antibody, IL-12.p40 antibody, IL12p40 antibody, IL12B antibody, CLMF p40 antibody, interleukin 12B antibody, interleukin 12b antibody, interleukin 12Ba antibody, IL12B antibody, Il12b antibody, il12ba antibody
    背景
    Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, Interleukin-12B, NK cell stimulatory factor chain 2, NKSF2
    基因ID
    281857
    途径
    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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