Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
1.0 mg/mL
缓冲液
PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
抗原
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
别名
Insulin Promoter Factor 1
背景
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).Synonyms: GSF, Glucose-sensitive factor, IDX-1, IPF-1, IPF1, IUF-1, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, PDX-1, PDX1, Pancreas/duodenum homeobox protein 1, STF-1, Somatostatin-transactivating factor 1