IL1RL1 抗体
Quick Overview for IL1RL1 抗体 (ABIN1107729)
抗原
See all IL1RL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with ST2 antigen.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein A agarose
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免疫原
- Transmembrane receptor form of human ST2 (ST2L) transfected COS7 cells
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亚型
- IgG1
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anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 162-349) antibody
IL1RL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) antibodyIL1RL1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal ST33868 unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) antibodyIL1RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 207-220) antibodyIL1RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 38-87) antibodyIL1RL1 适用: 人, 小鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) antibodyIL1RL1 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) antibodyIL1RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 357-532) antibodyIL1RL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor-Like 1 (IL1RL1) (N-Term) antibodyIL1RL1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
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别名
- IL1RL1 / ST2
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背景
- The ST2 gene, also known as T1, Fit1, or DER4, was originally identified as a responsive gene that was highly induced by stimulation of various proliferation-inducing agents including serum, PDGF (platelet-derived growth factor), FGF (fibroblast growth factor), or lysophosphatidic acid in murine fibroblasts. Three distinct forms of gene products have been reported and named ST2, ST2V, and ST2L. ST2 is a soluble secreted form of 37 kDa protein, which lacks intracellular domain, whereas ST2L is a transmembrane form of 62 kDa protein (the glycosylated forms of ST2 and ST2L are about 57 and 80 kDa, respectively). This ST2L protein is very similar to IL-1R (interleukin-1 receptor) type I and II in structure, thus it is considered as a member of the IL-1R family. ST2V, which is another novel variant form of human ST2, has been identified recently. ST2 proteins are expressed in the wide variety types of human cells, including hematopoietic cells in various stages of differentiation, a population of the peripheral blood mononuclear cells from healthy individuals, glioblastoma and astrocytoma cell lines, and colon cancer cells in addition to fibroblast cell lines. Thus ST2 proteins are considered to have some roles in regulating cell growth or proliferation. On the other hand, either definitive functions of ST2 proteins or their ligand molecule(s) which binds to ST2 proteins have remained unclear, though it has been reported that none of IL-1a, ß, RA (receptor antagonist) binds to ST2 proteins in spite of their structural similarity to IL-1R. This indicates that ST2L protein is functionally independent from IL-1R. Furthermore, several studies have shown that ST2L is expressed on the cell surface of Th2 cells but not on the Th1 cells, indicating the possibility that ST2L protein participates not only in the regulation of cell growth or proliferation, but also in the immune system including differentiation of T cells or immunological response via helper T cells. From these observations, ST2 proteins are considered to be one of the important proteins participate in various physiological phenomenon, thus further analysis are required to understand its physiological functions.Synonyms: DER4, FIT-1, Homolog of mouse growth stimulation-expressed, Interleukin-1 receptor-like 1, MGC32623
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基因ID
- 9173
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NCBI登录号
- NP_003847
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UniProt
- Q01638
抗原
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