IFNA2 抗体
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北京 101111
Quick Overview for IFNA2 抗体 (ABIN1107639)
抗原
See all IFNA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to IFN-alpha (II).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Purified
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免疫原
- A BALB/c mouse was immunized with E-coli derived, purified recombinant IFN-alpha 2c and spleen cells were fused with mouse myeloma cells NS1.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0,1 mg/mL
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缓冲液
- PBS, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IFNA2 (Interferon, alpha 2 (IFNA2))
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别名
- IFNA2 / Interferon alpha-2
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背景
- The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNalppha family has over .. genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNalpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNalpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNalpha are now known and seem to be expressed on most cell types. N39 is specific for INFalpha(II) and does not crossreact with INFalpha(I).Synonyms: IFN-alpha 2, Interferon alpha-A, LeIF A
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基因ID
- 3440
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NCBI登录号
- NP_000596
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UniProt
- P01563
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
抗原
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