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IFNA1 抗体

IFNA1 适用: 小鼠 FACS, Func, EIA 宿主: 大鼠 Monoclonal F18 unconjugated
产品编号 ABIN1107635
发货至: 中国
  • 抗原 See all IFNA1 抗体
    IFNA1 (Interferon, alpha 1 (IFNA1))
    适用
    • 69
    • 13
    • 3
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 51
    • 21
    • 3
    大鼠
    克隆类型
    • 53
    • 22
    单克隆
    标记
    • 36
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFNA1 antibody is un-conjugated
    应用范围
    • 38
    • 30
    • 14
    • 14
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognises most isoforms of natural and recombinant alpha Interferon. It does not cross-react with Murine beta or gamma Interferon, nor with Human alpha Interferon. The antibody exhibits neutralizing activity of approximately 6.25 x 10e4 neutralizing units/mg.
    交叉反应 (详细)
    Species reactivity (tested):Mouse.
    纯化方法
    Protein G
    克隆位点
    F18
    亚型
    IgG1
    Top Product
    Discover our top product IFNA1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.1 % BSA
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    有效期
    6 months
  • 抗原
    IFNA1 (Interferon, alpha 1 (IFNA1))
    别名
    IFNA1 / Interferon-alpha 1 (IFNA1 产品)
    别名
    IFL antibody, IFN antibody, IFN-ALPHA antibody, IFN-alphaD antibody, IFNA13 antibody, IFNA@ antibody, Ifa1 antibody, IFN-ALPHA-1 antibody, IFN1@ antibody, IFNA1 antibody, IFN-alpha antibody, IFN-gamma antibody, IFNA antibody, IFNA2 antibody, IFNA6 antibody, IFN-alpha1 antibody, interferon alpha 13 antibody, interferon alpha 1 antibody, interferon, alpha 1 antibody, interferon, alpha 13 antibody, interferon antibody, interferon-alpha 1 antibody, interferon, alpha, leukocyte antibody, interferon-alpha-14 antibody, IFNA13 antibody, IFNA1 antibody, Ifna1 antibody, ifna1 antibody, IFNA3 antibody, IFN-ALPHA-14 antibody
    背景
    The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response, it modulates adaptive immunity. The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: IFN-alpha 1, IFNA13, Interferon alpha-D, LeIF D
    基因ID
    15962
    NCBI登录号
    NP_034632
    UniProt
    P01572
    途径
    JAK/STAT Signaling, Hepatitis C
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