HTRA2 抗体
(1 reference)Our Local Distributor
北京 101111
Quick Overview for HTRA2 抗体 (ABIN1107619)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody reacts with HtrA2/Omi (40 kDa) on Western blotting.
-
纯化方法
- Protein-A Agarose Chromatography of hybridoma supernatant.
-
免疫原
- Human recombinant 6His tagged HtrA2/Omi.
-
亚型
- IgG2a
-
-
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 278-458) antibody
HTRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6H7A8 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 334-458) antibodyHTRA2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 359-458) antibodyHTRA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (C-Term) antibodyHTRA2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 231-330) antibodyHTRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6110 unconjugated Recombinant Antibody
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 8G11-4B8-4F10-G5 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (C-Term) antibodyHTRA2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 335-350) antibodyHTRA2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 196C429 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 73-102), (N-Term) antibodyHTRA2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33645 unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
-
储存液
- Without preservative
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody (in aliquots) at -20 °C.
-
-
-
: "Neuroprotective function of Omi to α-synuclein-induced neurotoxicity." in: Neurobiology of disease, Vol. 136, pp. 104706, (2021) (PubMed).
-
: "Neuroprotective function of Omi to α-synuclein-induced neurotoxicity." in: Neurobiology of disease, Vol. 136, pp. 104706, (2021) (PubMed).
-
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
-
别名
- HTRA2 / PRSS25
-
背景
- HtrA2, also known as Omi or Serine Protease-25, is a trimeric chaperone/heat shock protein involved in the degradation of aberrantly folded proteins during cellular stress. The ubiquitous HtrA2 protein exists as two isoforms of 38 and 40 kDa and as an alternatively spliced form called D-Omi, which is predominately expressed in the kidney, colon and thyroid. HtrA2 appears to function in the progression of arthritis, aging, and tumor progression. During apoptosis, HtrA2 is released from mitochondria into the cytoplasm where it inhibits XIAP, a caspase inhibitor. Release of HtrA2 from mitochondria appears to require Bax and Bcl-2, and the resulting overexpression of HtrA2 into the cytoplasm induces caspase-independent apoptosis.Synonyms: High temperature requirement protein A2, OMI, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, mitochondrial Serine protease HTRA2
-
基因ID
- 27429
-
NCBI登录号
- NP_037379
-
UniProt
- O43464
-
途径
- Positive Regulation of Endopeptidase Activity
抗原
-
